GLMN antibody (N-Term)

Catalog No. ABIN406218

Product Details anti-GLMN Antibody

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLMN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AVEELQSIIK RCQILEEQDF KEEDFGLFQL AGQRCIEEGH TDQLLEIIQN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GLMN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLMN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 594 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Alternative Name: GLMN (GLMN Products)

Background: GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM
Protein Interaction Partner: UBC, CDC37L1, CDC37, FKBP5, FKBP4, SAV1, FBXW7, RBX1, RNF7, CUL1, SKP1, EIF3A, CUL2, CUL3, CUL4A, TMEM173, NSFL1C, FKBP1A, MET,
Protein Size: 594

Molecular Weight: 68 kDa

Gene ID: 11146

NCBI Accession: NM_053274, NP_444504

UniProt: Q92990

Pathways: Tube Formation