MRPL39 antibody (N-Term)

Catalog No. ABIN405805

Product Details anti-MRPL39 Antibody

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TELTEMRNDL FNKEKARQLS LTPRTEKIEV KHVGKTDPGT VFVMNKNIST

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MRPL39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL39

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MRPL39 (MRPL39 Products)

Background: Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL39 is a 39S subunit protein. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.
Alias Symbols: C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5, MRPL5
Protein Interaction Partner: TP53, UBC, SOX2, NPM1, MRPL55, MRPL52, MRPL24, MRPL44, MRPL9, MRPL11, MRPL32, MRPL38, MRPL40, MRPS9, MRPL14, MARC1, TSR1, MRPL37, MRPL15, MRPL13, MRPL3, MRPL19, LAMTOR3, NONO, ILF3, ICT1, DLST, MRPL49, CAND1, CUL3, TCF3, USP32, PAN2,
Protein Size: 338

Molecular Weight: 39 kDa

Gene ID: 54148

NCBI Accession: NM_017446, NP_059142

UniProt: Q9NYK5