MAP4K1 antibody (N-Term)

Catalog No. ABIN405785

Product Details anti-MAP4K1 Antibody

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VHPLRVLFLM TKSGYQPPRL KEKGKWSAAF HNFIKVTLTK SPKKRPSATK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MAP4K1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 821 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP4K1

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Alternative Name: MAP4K1 (MAP4K1 Products)

Background: MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
Alias Symbols: HPK1
Protein Interaction Partner: FBXW7, FBXW8, MAP4K1, UBC, SKP1, PPP4C, RBX1, CUL7, TMEM101, HSP90AA1, NCK1, LRRK1, SPRY1, GRAP2, COPS5, DBNL, DAPP1, BLNK, MAP3K7, LAT, CRKL, LCP2, HCLS1, CASP3, SHC1, SYK, MAP3K11, ABL1, LYN, CRK, EGFR, GRB2,
Protein Size: 821

Molecular Weight: 90 kDa

Gene ID: 11184

NCBI Accession: NM_001042600, NP_001036065

UniProt: A8MWC4

Pathways: TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor