SPOCK3 antibody (Middle Region)

Catalog No. ABIN405715

Product Details anti-SPOCK3 Antibody

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPOCK3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CPCPSDKPTS TSRNVKRACS DLEFREVANR LRDWFKALHE SGSQNKKTKT

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SPOCK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPOCK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SPOCK3 antibody (ABIN405715)

Lutter, Xie, Tatin, Makinen: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." in: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).

Target Details for SPOCK3

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Alternative Name: SPOCK3 (SPOCK3 Products)

Background: Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 is a member of a novel Ca(2+)-binding proteoglycan familyProteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM].
Alias Symbols: HSAJ1454, TES-3, TICN3
Protein Interaction Partner: SPOCK2, MMP14, MMP3,
Protein Size: 433

Molecular Weight: 49 kDa

Gene ID: 50859

NCBI Accession: NM_001040159, NP_001035249

UniProt: B3KR67

Pathways: Glycosaminoglycan Metabolic Process