Podoplanin antibody (Middle Region)

Catalog No. ABIN405667

Product Details anti-Podoplanin Antibody

Target: Podoplanin (PDPN)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VATSHSTEKV DGDTQTTVEK DGLSTVTLVG IIVGVLLAIG FIGAIIVVVM

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PDPN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDPN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: PDPN (PDPN Products)

Background: PDPN is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, AGGRUS
Protein Interaction Partner: TOM1L1,
Protein Size: 238

Molecular Weight: 25 kDa

Gene ID: 10630

NCBI Accession: NM_006474, NP_006465

Pathways: Dicarboxylic Acid Transport