SLC8A3 antibody (N-Term)

Catalog No. ABIN405619

Product Details anti-SLC8A3 Antibody

Target: SLC8A3 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC8A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SAPEILLSLI EVCGHGFIAG DLGPSTIVGS AAFNMFIIIG ICVYVIPDGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC8A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC8A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 925 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC8A3 antibody (ABIN405619)

Heise, Shumilina, Nurbaeva, Schmid, Szteyn, Yang, Xuan, Wang, Zemtsova, Duszenko, Lang: "Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells." in: American journal of physiology. Cell physiology, Vol. 300, Issue 6, pp. C1306-13, (2011) (PubMed).

Target Details for SLC8A3

Target: SLC8A3 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3))

Alternative Name: SLC8A3 (SLC8A3 Products)

Background: SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner.This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Alias Symbols: NCX3
Protein Interaction Partner: YWHAE, YWHAB, YWHAQ, PPP3CB,
Protein Size: 925

Molecular Weight: 103 kDa

Gene ID: 6547

NCBI Accession: NM_033262, NP_150287

UniProt: Q96QG2