SLC39A7 antibody (N-Term)

Catalog No. ABIN405594

Product Details anti-SLC39A7 Antibody

Target: SLC39A7 (Solute Carrier Family 39 (Zinc Transporter), Member 7 (SLC39A7))

Binding Specificity: N-Term

Reactivity: Human, Dog, Pig, Rabbit, Sheep, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HDHEHSHGGY GESGAPGIKQ DLDAVTLWAY ALGATVLISA APFFVLFLIP

Predicted Reactivity: Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against SLC39A7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 469 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC39A7 antibody (ABIN405594)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for SLC39A7

Target: SLC39A7 (Solute Carrier Family 39 (Zinc Transporter), Member 7 (SLC39A7))

Alternative Name: SLC39A7 (SLC39A7 Products)

Background: Zinc is an essential cofactor for more than 50 classes of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. Zinc cannot passively diffuse across cell membranes and requires specific transporters, such as SLC39A7, to enter the cytosol from both the extracellular environment and from intracellular storage compartments.Zinc is an essential cofactor for more than 50 classes of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. Zinc cannot passively diffuse across cell membranes and requires specific transporters, such as SLC39A7, to enter the cytosol from both the extracellular environment and from intracellular storage compartments.[supplied by OMIM].
Alias Symbols: D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7
Protein Interaction Partner: UBC, SUZ12, BMI1, YY1, SUMO1, USP49, RGS20, CD40,
Protein Size: 469

Molecular Weight: 50 kDa

Gene ID: 7922

NCBI Accession: NM_001077516, NP_001070984

UniProt: Q92504

Pathways: Transition Metal Ion Homeostasis