ELMO3 antibody (Middle Region)

Catalog No. ABIN405491

Product Details anti-ELMO3 Antibody

Target: ELMO3 (Engulfment and Cell Motility 3 (ELMO3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RKLGFSNSNP AQDLERVPPG LLALDNMLYF SRNAPSAYSR FVLENSSRED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ELMO3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELMO3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 773 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELMO3

Target: ELMO3 (Engulfment and Cell Motility 3 (ELMO3))

Alternative Name: ELMO3 (ELMO3 Products)

Background: ELMO3 is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.
Alias Symbols: CED-12, CED12, ELMO-3, FLJ13824
Protein Interaction Partner: UBC,
Protein Size: 773

Molecular Weight: 87 kDa

Gene ID: 79767

NCBI Accession: NM_024712, NP_078988

UniProt: Q96BJ8