SFRS2B antibody (Middle Region)

Catalog No. ABIN405374

Product Details anti-SFRS2B Antibody

Target: SFRS2B (SRSF8) (serine/arginine-Rich Splicing Factor 8 (SRSF8))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YRESRYGGSH YSSSGYSNSR YSRYHSSRSH SKSGSSTSSR SASTSKSSSA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRS2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRS2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 282 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SFRS2B

Target: SFRS2B (SRSF8) (serine/arginine-Rich Splicing Factor 8 (SRSF8))

Alternative Name: SFRS2B (SRSF8 Products)

Background: The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. SFRS2B is a member of the SR family and functions as an essential splicing factor in vitro.The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The protein encoded by this gene is a member of the SR family and functions as an essential splicing factor in vitro. This gene is thought to be an expressed PR264/SC35 retropseudogene.
Alias Symbols: SRP46, SFRS2B
Protein Interaction Partner: SUZ12, EED, SRPK2, SRPK1, IGSF8, CD81, PAN2, UBC, MAGOH, APP, YWHAZ, ELAVL1, SREK1,
Protein Size: 282

Molecular Weight: 32 kDa

Gene ID: 10929

NCBI Accession: NM_032102, NP_115285

UniProt: Q9BRL6