GTF2E2 antibody (Middle Region)

Catalog No. ABIN405138

Product Details anti-GTF2E2 Antibody

Target: GTF2E2 (General Transcription Factor IIE, Polypeptide 2 (GTF2E2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2E2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ISSMQESGPK KVAPIQRRKK PASQKKRRFK THNEHLAGVL KDYSDITSSK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTF2E2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF2E2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 291 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2E2

Target: GTF2E2 (General Transcription Factor IIE, Polypeptide 2 (GTF2E2))

Alternative Name: GTF2E2 (GTF2E2 Products)

Background: GTF2E2 belongs to the TFIIE beta subunit family.It recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Alias Symbols: FE, TF2E2, TFIIE-B
Protein Interaction Partner: UBC, PBDC1, SEC24D, MMS19, MCC, CDK7, GTF2E1, APP, tat, ATF7IP, EXOC4, UBR5, MTA2, TPR, HSP90AB1, HNRNPA1, DNM2, SUPT16H, CCNH, GTF2B, NUP62, KLF5, MNAT1, SND1, GTF2A1, TBP, XPA, GTF2H1, GTF2F2, GTF2F1, MDM2, ERCC6, ERCC3, JUN, GTF2E2, FOS, POLR2A,
Protein Size: 291

Molecular Weight: 33 kDa

Gene ID: 2961

NCBI Accession: NM_002095, NP_002086

UniProt: P29084