SLC18A1 antibody (Middle Region)

Catalog No. ABIN405007

Product Details anti-SLC18A1 Antibody

Target: SLC18A1 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 1 (SLC18A1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC18A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YYLRSPPAKE EKLAILSQDC PMETRMYATQ KPTKEFPLGE DSDEEPDHEE

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 91%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SLC18A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC18A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 525 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC18A1

Target: SLC18A1 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 1 (SLC18A1))

Alternative Name: SLC18A1 (SLC18A1 Products)

Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazineThe vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CGAT, VAT1, VMAT1
Protein Size: 525

Molecular Weight: 56 kDa

Gene ID: 6570

NCBI Accession: NM_003053, NP_003044

UniProt: P54219