YBX2 antibody (N-Term)

Catalog No. ABIN404943

Product Details anti-YBX2 Antibody

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EPQKGGGAGG GGGAASGPAA GTPSAPGSRT PGNPATAVSG TPAPPARSQA

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against YBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YBX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 364 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YBX2

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Alternative Name: YBX2 (YBX2 Products)

Background: YBX2 is a member of the Y box multigene family of proteins, it contains the cold shock domain that is highly conserved among all Y box proteins and four basic/aromatic islands. By Northern blotting and immunoblotting, MSY2 appears to be a germ cell-specific protein in the testis. In the ovary, MSY2 is present exclusively in diplotene-stage and mature oocytes. MSY2 is maternally inherited in the one-cell-stage embryo but is not detected in the late two-cell-stage embryo. This loss of MSY2 is coincident with the bulk degradation of maternal mRNAs in the two-cell embryo. YBX2 is a germ-cell specific member of the vertebrate Y box family of nucleic acid-binding proteins (Gu et al., 1998 [PubMed 9780336], Tekur et al., 1999 [PubMed 10100484]).[supplied by OMIM].
Alias Symbols: CSDA3, MGC45104, MSY2, DBPC, CONTRIN
Protein Interaction Partner: IGSF8, HDAC11, ICAM1, UBC,
Protein Size: 364

Molecular Weight: 38 kDa

Gene ID: 51087

NCBI Accession: NM_015982, NP_057066

UniProt: Q9Y2T7

Pathways: Chromatin Binding