RNASET2 antibody (Middle Region)

Catalog No. ABIN404853

Product Details anti-RNASET2 Antibody

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASET2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RSRFWKHEWE KHGTCAAQVD ALNSQKKYFG RSLELYRELD LNSVLLKLGI

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%, Rat: 75%

Characteristics: This is a rabbit polyclonal antibody against RNASET2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNASET2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 256 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RNASET2 antibody (ABIN404853)

Campomenosi, Salis, Lindqvist, Mariani, Nordström, Acquati, Taramelli: "Characterization of RNASET2, the first human member of the Rh/T2/S family of glycoproteins." in: Archives of biochemistry and biophysics, Vol. 449, Issue 1-2, pp. 17-26, (2006) (PubMed).

Target Details for RNASET2

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Alternative Name: RNASET2 (RNASET2 Products)

Background: This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement.This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
Alias Symbols: RNASE6PL, bA514O12.3, RP11-514O12.3
Protein Interaction Partner: FBXO6, UBC, NIT2, PRDX3, SLC9A3R1, SUCLG2, MRPL12, NDUFV1,
Protein Size: 256

Molecular Weight: 29 kDa

Gene ID: 8635

NCBI Accession: NM_003730, NP_003721

UniProt: O00584