PBXIP1 antibody (N-Term)

Catalog No. ABIN404836

Product Details anti-PBXIP1 Antibody

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBXIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGGEGAGGEL GISLNMCLLG ALVLLGLGVL LFSGGLSESE TGPMEEVERQ

Predicted Reactivity: Cow: 92%, Human: 100%, Mouse: 92%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PBXIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBXIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 731 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PBXIP1

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Alternative Name: PBXIP1 (PBXIP1 Products)

Background: PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
Alias Symbols: HPIP
Protein Interaction Partner: MORF4L1, SGTA, GMCL1, DEF6, UBQLN1, DAXX, CCNC, UBC, SUMO1, NEDD8, RNF2, CCDC53, ZMYND8, MDFI, UBQLN4, PRKAA2, GRB2, PCBD2, ZZZ3, BRPF1, CCDC85B, DPPA2, TSNAX,
Protein Size: 731

Molecular Weight: 81 kDa

Gene ID: 57326

NCBI Accession: NM_020524, NP_065385

UniProt: Q96AQ6