CD22 antibody
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- Target See all CD22 Antibodies
- CD22 (CD22 Molecule (CD22))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD22 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Characteristics
- Synonyms: SIGLEC2, Siglec-2, B-cell receptor CD22, Leu-14, BL-CAM, Sialic acid-binding Ig-like lectin 2,B-lymphocyte cell adhesion molecule
- Purification
- Protein A affinity chromatography
- Purity
- > 95 % by SDS-PAGE
- Immunogen
- Reh human cell line
- Clone
- IS7
- Isotype
- IgG1
- Top Product
- Discover our top product CD22 Primary Antibody
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reactivity: Human FACS, WB, ELISA, IHC, ICC Host: Mouse Monoclonal 2H1C4 unconjugated
anti-CD22 Molecule (CD22) (AA 621-725) antibodyCD22 Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 1A3A11 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivity: Human FACS, WB, ELISA, IHC, IF, Coat, StM Host: Mouse Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivity: Human FACS, WB, ELISA, IHC, IF, Coat Host: Mouse Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivity: Human, Non-Human Primate FACS, WB, IP Host: Mouse Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reactivity: Human FACS Host: Mouse Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) (AA 20-687) antibodyCD22 Reactivity: Human FACS, WB, ELISA, IF, IP Host: Rabbit Monoclonal DM13 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivity: Human, Mouse, Rat, Monkey, Dog WB, IHC, IHC (p) Host: Mouse Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Flow Cytometry. Positive control: lysed whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized.
- Preservative
- Azide free
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD22 (CD22 Molecule (CD22))
- Alternative Name
- CD22 (CD22 Products)
- Background
- CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.Synonyms: B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14, SIGLEC2, Sialic acid-binding Ig-like lectin 2, Siglec-2
- UniProt
- P20273
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