CMV gB antibody
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- Target
- CMV gB
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Reactivity
- Human Herpesvirus 5 (HHV-5)
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)
- Specificity
- Detects cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kD. Does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells. Has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures.
- Purification
- Affinity purified
- Immunogen
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Native.
Type of Immunogen: Native protein - Clone
- HCMV34
- Isotype
- IgG2a
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- Application Notes
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Approved: ELISA, IF, IHC, IHC-Fr
Usage: Immunohistology: Reactive only in acetone fixed CMV infected cells or frozen sections. - Comment
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Target Species of Antibody: Cytomegalovirus
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Target
- CMV gB
- Target Type
- Viral Protein
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