Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This YES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human YES1.
YES is a member of the Src family of non-receptor tyrosine kinases participating in a wide range of cellular signalling pathways. The gene that encodes YES is the cellular homolog of the Yamaguchi sarcoma virus oncogene. This gene lies in proximity to thymidylate synthase gene on chromosome 18, and a pseudogene of it has mapped to chromosome 22.