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DDR1 antibody

DDR1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14725 unconjugated
Catalog No. ABIN392016
  • Target See all DDR1 Antibodies
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Reactivity
    • 79
    • 34
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 86
    • 8
    Rabbit
    Clonality
    • 85
    • 8
    • 1
    Polyclonal
    Conjugate
    • 45
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This DDR1 antibody is un-conjugated
    Application
    • 73
    • 36
    • 26
    • 26
    • 19
    • 12
    • 10
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MCK10 antibody is generated from rabbits immunized with recombinant human MCK10 protein.
    Clone
    RB14725
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DDR1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Alternative Name
    MCK10 (DDR1 Products)
    Background
    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.
    Molecular Weight
    101128
    Gene ID
    780
    NCBI Accession
    NP_001189450, NP_001189451, NP_001189452, NP_001945, NP_054699, NP_054700
    UniProt
    Q08345
    Pathways
    RTK Signaling, Smooth Muscle Cell Migration
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