VEGFD (VEGF4) (AA 322-352), (C-Term) antibody

Catalog No. ABIN390256

Product Details

Target: VEGFD (VEGF4)

Binding Specificity: AA 322-352, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This VEGFD (VEGF4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human VEGFD (VEGF4).

Clone: RB11698

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References

Dai, Liu, Liu, Zhang, Wang, Jin, Qian, Wang, Zhao, Wu, Xiong, Chang, Sun, Yang, Hoffman, Liu: "Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model." in: Anticancer research, Vol. 37, Issue 3, pp. 979-986, (2017) (PubMed).

Target Details

Target: VEGFD (VEGF4)

Background: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.

Molecular Weight: 40444

Gene ID: 2277

NCBI Accession: NP_004460

UniProt: O43915