APG8b (AA 74-106) antibody

Catalog No. ABIN388476

Product Details

Target: APG8b

Binding Specificity: AA 74-106

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APG8b (MAP1LC3B)-T93/Y99 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-106 amino acids from the Central region of human APG8b (MAP1LC3B)-T93/Y99.

Clone: RB17597

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

Expiry Date: 6 months

References

Won, Yen, Lin, Jiang-Shieh, Lin, Chen, Su: "Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 497-505, (2017) (PubMed).

Target Details

Target: APG8b

Alternative Name: APG8b (MAP1LC3B)

Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Molecular Weight: 14688

Gene ID: 81631

NCBI Accession: NP_073729

UniProt: Q9GZQ8