Calmodulin 1 antibody (C-Term)

Catalog No. ABIN388399

Product Details anti-Calmodulin 1 Antibody

Target: Calmodulin 1 (Calm1)

Binding Specificity: AA 117-149, C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: X, B, C, Zf, Rb, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Calmodulin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-149 amino acids from the C-terminal region of human Calmodulin.

Clone: RB00561

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Calmodulin 1 antibody (ABIN388399)

Chan, Vuckovic, Sleno, Olsen, Pogoutse, Havugimana, Hewel, Bajaj, Wang, Musteata, Nislow, Emili: "Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016642, (2012) (PubMed).

Target Details for Calmodulin 1

Target: Calmodulin 1 (Calm1)

Alternative Name: Calmodulin (Calm1 Products)

Background: Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.

Gene ID: 808

NCBI Accession: NP_001734, NP_005175, NP_008819

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling