FAS antibody (APC)
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- Target See all FAS Antibodies
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FAS antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Specificity
- Human/Rhesus/African Green Monkey/Sooty Mangabey CD95, Mr 45 kDa
- Characteristics
- Mouse Anti-Human CD95-APC
- Purification
- Purified
- Immunogen
- Human CD95 transfected L cells
- Clone
- DX2
- Isotype
- IgG1
- Top Product
- Discover our top product FAS Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Apop - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, AF488 and AF647 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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in vivo induction of apoptosis
- Restrictions
- For Research Use only
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- Buffer
- 25 tests in 0.25 mL or 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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- Target
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Alternative Name
- CD95 (FAS Products)
- Background
- CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance.
- Pathways
- p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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