CES1 antibody (Internal Region)

Catalog No. ABIN375109

Product Details anti-CES1 Antibody

Target: CES1 (Carboxylesterase 1 (CES1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to CES1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-NTQAAQKLKDKE, from the internal region (near C terminus) of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 0.03 - 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1 / ACAT (CES1 Products)

Background: The enzymes of the carboxylesterase family are widely distributed and can be found in the tissues of all animals. They differ in biochemical, immunological and genetic properties and play different roles depending on which part of the organism they are expressed in. In general, these carboxylesterases are responsible for detoxification, since they are able to degrade a number of exogenous compounds such as esters, amides and thioesters.Synonyms: Acyl coenzyme A:cholesterol acyltransferase, Brain carboxylesterase hBr1, CES2, Egasyn, HMSE, Liver carboxylesterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, SES1, Serine esterase 1, Triacylglycerol hydrolase, hBr1

Gene ID: 1066, 9606

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process