EWSR1 antibody (Internal Region)
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- Target See all EWSR1 Antibodies
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Cow
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This EWSR1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequence
- C-TSYDQSSYSQ QNTYG
- Specificity
- This antibody is expected to recognize all five reported isoforms.
- Cross-Reactivity (Details)
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Species reactivity (expected):Bovine, Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_053733.2, NP_005234.1, NP_001156757.1, NP_001156758.1, NP_001156759.1. Genename: EWSR1
- Top Product
- Discover our top product EWSR1 Primary Antibody
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- Application Notes
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
- Alternative Name
- EWSR1 (EWSR1 Products)
- Background
- EWSR1 is a putative RNA binding protein of unknown function. Mutations in this gene, specifically at (11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.Synonyms: EWS, EWS oncogene, EWSR-1, Ewing sarcoma breakpoint region 1 protein, RNA-binding protein EWS
- Gene ID
- 2130, 9606
- UniProt
- Q01844
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