AIP antibody (C-Term)

Catalog No. ABIN374759

Product Details anti-AIP Antibody

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This AIP antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody recognizes AIP/ARA9.

Cross-Reactivity (Details): Species reactivity (expected):Rat and Canine.
Species reactivity (tested):Human and Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-EARIRQKDEEDKAR, from the C Terminus of the protein sequence according to NP_003968.1

Application Details

Application Notes: Peptide ELISA: Detection limit dilution: 1/64000. Western Blot: 0.02-0.06 μg/mL. Approx 37 kDa band observed in lysates of cell line NIH/3T3. In transfected HEK293 transiently expressing ARA9 a band of approx.47 kDa is observed. This band is not observed in the non-transfected HEK293.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 vcontaining 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AIP

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Alternative Name: AIP / XAP2 (AIP Products)

Synonyms: AIP antibody, xaip antibody, ARA9 antibody, FKBP16 antibody, FKBP37 antibody, SMTPHN antibody, XAP-2 antibody, XAP2 antibody, wu:fa03h10 antibody, zgc:101101 antibody, AA408703 antibody, AW476050 antibody, Ara9 antibody, D19Bwg1412e antibody, Fkbp16 antibody, Xap2 antibody, aryl hydrocarbon receptor interacting protein antibody, aryl-hydrocarbon receptor-interacting protein antibody, AIP antibody, aip antibody, Aip antibody

Background: ARA9 displays structural similarity to the glucocorticoid receptor-associated immunophilin FKBP52. Although they share significant homology, they have distinct cellular roles and biochemical properties. ARA9 is known to affect the potency and efficacy of AHR agonists in the yeast S. cerevisiae as well as having functional consequences on AHR signal transduction.Synonyms: AH receptor-interacting protein, ARA9, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, Immunophilin homolog ARA9

Gene ID: 9049, 9606

UniProt: O00170