CCM2 antibody (Internal Region)

Catalog No. ABIN374751

Product Details anti-CCM2 Antibody

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This CCM2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Malcavernin.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-KGEKSRDKKAHEK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody in aliquots at -20 °C.

Target Details for CCM2

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Alternative Name: Malcavernin (CCM2 Products)

Background: CCM2 may function as a scaffold protein for MAP2K3-MAP3K3 signaling. It seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.Synonyms: C7orf22, CCM2, Cerebral cavernous malformations 2 protein, PP10187

Gene ID: 83605, 9606

UniProt: Q9BSQ5

Pathways: Cell-Cell Junction Organization