NMDA 1 Receptor antibody (Internal Region)

Catalog No. ABIN374717

Product Details anti-NMDA 1 Receptor Antibody

Target: NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This NMDA 1 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to all three reported isoforms of NMDAR1.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Canine.
Species reactivity (tested):Rat.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-TQERVNNSNKKE, from the internal region of the protein sequence

Application Details

Application Notes: ELISA: 1/1000. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NMDA 1 Receptor

Target: NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))

Alternative Name: NMDA Receptor 1 (NMDA R1 Products)

Background: NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1

Gene ID: 2902, 9606

UniProt: Q05586