WT1 antibody (N-Term)
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- Target See all WT1 Antibodies
- WT1 (Wilms Tumor 1 (WT1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This WT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody reacts to Wilms tumor 1. This antibody is expected to recognise all four reported isoforms.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography
- Immunogen
- Peptide with sequence QDPASTCVPEPASQH, from the N Terminus of the protein sequence
- Top Product
- Discover our top product WT1 Primary Antibody
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- Application Notes
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ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- WT1 (Wilms Tumor 1 (WT1))
- Alternative Name
- WT1 / Wilms Tumor Protein (WT1 Products)
- Background
- WT1 encodes multiple isoforms of a zinc finger transcription factor essential for correct mammalian urogenital development. Different WT1 isoforms are thought to regulate transcription and participate in mRNA processing, functions reflected by a complex sub nuclear distribution. In humans, the preservation of the correct isoform ratio and their localization has been reported to be vital, and its disruption to result in disease. This gene has been reported as a useful marker for several types of illnesses. Mutations in this gene lead to the development of Wilm's Tumor, a sporadic and familial childhood kidney tumor.Synonyms: WT33
- Gene ID
- 7490, 9606
- UniProt
- P19544
- Pathways
- Tube Formation
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