Melanoma gp100 antibody (C-Term)
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- Target See all Melanoma gp100 (PMEL) Antibodies
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Melanoma gp100 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody recognizes Silver homologue / Pmel17.
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography
- Immunogen
- Peptide with sequence CPIGENSPLLSGQQ, from the C Terminus of the protein sequence according to NP_008859.1
- Top Product
- Discover our top product PMEL Primary Antibody
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- Application Notes
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Alternative Name
- Melanoma Gp100 (PMEL Products)
- Background
- Melanoma gp100, a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.Synonyms: D12S53E, ME20-M, Melanocyte lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen, PMEL17, SILV, Silver locus protein homolog
- Molecular Weight
- 70.3kDa (NP_008859.1).
- Gene ID
- 6490
- NCBI Accession
- NP_001186982
- UniProt
- P40967
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