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CBX1 antibody (Internal Region)

CBX1 Reactivity: Human, Mouse, Rat, Dog WB, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN374618
  • Target See all CBX1 Antibodies
    CBX1 (Chromobox Homolog 1 (CBX1))
    Binding Specificity
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 44
    • 19
    • 16
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 32
    • 9
    • 2
    • 1
    Goat
    Clonality
    • 31
    • 12
    • 1
    Polyclonal
    Conjugate
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBX1 antibody is un-conjugated
    Application
    • 30
    • 23
    • 9
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to Chromobox protein homolog 1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-QSQKTAHETDKSE, from the internal region of the protein sequence
    Top Product
    Discover our top product CBX1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1.0 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CBX1 (Chromobox Homolog 1 (CBX1))
    Alternative Name
    CBX1 (CBX1 Products)
    Background
    Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.A component of heterochromatin HP1 recognizes and binds histone H3, leading to epigenetic repression. HP1 may interact with lamin B receptor (LBR), this interaction can contribute to the association of the heterochromatin with the inner nuclear membrane.Synonyms: Chromobox protein homolog 1, HP1 beta, HP1-beta, HP1Hsbeta, Heterochromatin protein 1 homolog beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
    Gene ID
    10951, 9606
    UniProt
    P83916
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