CBX1 antibody (Internal Region)
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- Target See all CBX1 Antibodies
- CBX1 (Chromobox Homolog 1 (CBX1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This CBX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody reacts to Chromobox protein homolog 1.
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogen
- Peptide with sequence C-QSQKTAHETDKSE, from the internal region of the protein sequence
- Top Product
- Discover our top product CBX1 Primary Antibody
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- Application Notes
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Peptide ELISA: 1/32000. Western Blot: 0.3 - 1.0 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CBX1 (Chromobox Homolog 1 (CBX1))
- Alternative Name
- CBX1 (CBX1 Products)
- Background
- Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.A component of heterochromatin HP1 recognizes and binds histone H3, leading to epigenetic repression. HP1 may interact with lamin B receptor (LBR), this interaction can contribute to the association of the heterochromatin with the inner nuclear membrane.Synonyms: Chromobox protein homolog 1, HP1 beta, HP1-beta, HP1Hsbeta, Heterochromatin protein 1 homolog beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
- Gene ID
- 10951, 9606
- UniProt
- P83916
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