Cofilin 2 antibody (C-Term)

Catalog No. ABIN374596

Product Details anti-Cofilin 2 Antibody

Target: Cofilin 2 (CFL2)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This Cofilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-DIKDRSTLGE K

Specificity: This antibody recognizes Cofilin-2 (C-term). It is expected to recognise both reported isoforms (NP_068733 and NP_619579).

Cross-Reactivity (Details): Species reactivity (expected):Canine, Porcine.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_068733.1, NP_619579.1. Genename: CFL2

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Cofilin 2

Target: Cofilin 2 (CFL2)

Alternative Name: Cofilin-2 (CFL2 Products)

Background: Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. Cofilin 2 is the muscle isoform.Synonyms: CFL2, Cofilin, Cofilin2, muscle isoform

Gene ID: 1073, 9606

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis