SCARF1 antibody (Internal Region)

Catalog No. ABIN374467

Product Details anti-SCARF1 Antibody

Target: SCARF1 (Acetyl LDL Receptor (SCARF1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SCARF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Sequence: SELDPKGQHV C

Specificity: This antibody is expected to recognize all reported isoforms of SCARF1. Epitope Epitope corresponding to aa 20-31, mapping to the mature Human SCARF1/SREC1 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003684.2, NP_663325.1, NP_663327.2. Genename: SCARF1

Application Details

Application Notes: Peptide ELISA: 1/64000. Western blot: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCARF1

Target: SCARF1 (Acetyl LDL Receptor (SCARF1))

Alternative Name: SCARF1 (SCARF1 Products)

Synonyms: SREC antibody, SREC-I antibody, SREC1 antibody, AA986099 antibody, mKIAA0149 antibody, scavenger receptor class F member 1 antibody, scavenger receptor class F, member 1 antibody, SCARF1 antibody, Scarf1 antibody

Background: SCARF1 is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: Acetyl LDL receptor, Endothelial cells scavenger receptor, KIAA0149, SREC, Scavenger receptor class F member 1

Gene ID: 8578

NCBI Accession: NP_003684

UniProt: Q14162