CORO1C antibody (C-Term)

Catalog No. ABIN374431

Product Details anti-CORO1C Antibody

Target: CORO1C (Coronin, Actin Binding Protein, 1C (CORO1C))

Binding Specificity: C-Term

Reactivity: Human, Cow, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This CORO1C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-RISKLEQQMA KIAA

Specificity: This antibody recognizes Coronin 3/Coronin 1C.

Cross-Reactivity (Details): Species reactivity (expected):Pig and Cow.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_055140.1.

Application Details

Application Notes: Peptide ELISA: 1/64000. Western blot: 0.2-1.0 μg/mL. Approx 55 kDa band observed in human lung and placentalysates (predicted MW of 55 kDa according to NP_055140).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Target Details for CORO1C

Target: CORO1C (Coronin, Actin Binding Protein, 1C (CORO1C))

Alternative Name: Coronin-1C (CORO1C Products)

Background: Coronin 3 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). These may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. By similarity, Coronin 3 may be involved in cytokinesis, motility, and signal transduction. Coronin 3 is ubiquitously expressed in all human tissues, in contrast to other known coronin-like molecules, each of which is expressed in a tissue-specific manner.Synonyms: CORO1C, CRNN4, Coronin-3, hCRNN4

Gene ID: 23603

NCBI Accession: NP_055140

UniProt: Q9ULV4