TRF2 antibody (C-Term)

Catalog No. ABIN374265

Product Details anti-TRF2 Antibody

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This TRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-QIYPFVFESR KEIL

Specificity: This antibody detects TERF2 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Dog, CowSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_004856.1 Genename: TBPL1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 20 kDa band seen in Jurkat lysate [Predicted MW of 20 kDaaccording to NP_004856].
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2 (TERF2 Products)

Background: Synonyms: TRBF2, TRF2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein, Telomeric repeat-binding factor 2

Gene ID: 7014

NCBI Accession: NP_004856

UniProt: Q15554

Pathways: Cell Division Cycle, Telomere Maintenance