RPS6KA3 antibody (C-Term)
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- Target See all RPS6KA3 Antibodies
- RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Chicken
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RPS6KA3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody recognizes the ~90k RSK2 protein.
- Cross-Reactivity (Details)
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Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography.
- Immunogen
- Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).
- Isotype
- IgG
- Top Product
- Discover our top product RPS6KA3 Primary Antibody
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) antibody
RPS6KA3 Reactivity: Human WB, ELISA, FACS, ICC Host: Mouse Monoclonal 4E10 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 1-740) antibodyRPS6KA3 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 2-95) antibodyRPS6KA3 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 2G10 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (Center) antibodyRPS6KA3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 214-431) antibodyRPS6KA3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (pThr573) antibodyRPS6KA3 Reactivity: Human, Mouse ELISA, IF (p), IF (cc), IHC (p), IHC (fro), FACS Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (pSer227) antibodyRPS6KA3 Reactivity: Human, Rat ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (pTyr529) antibodyRPS6KA3 Reactivity: Human, Mouse ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) antibodyRPS6KA3 Reactivity: Human, Mouse, Monkey WB, IP Host: Mouse Monoclonal 6B9-D6-F8 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 13-42), (N-Term) antibodyRPS6KA3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB12516 unconjugated
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- Application Notes
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Target
- RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
- Alternative Name
- RPS6KA3 / RSK2 (RPS6KA3 Products)
- Background
- The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3
- Gene ID
- 6197
- NCBI Accession
- NP_004577
- UniProt
- P51812
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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