Calretinin antibody

Catalog No. ABIN372593

Product Details anti-Calretinin Antibody

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Human, Rat, Mouse, Non-Human Primate

Host: Sheep

Clonality: Polyclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Specific for the ~29 kDa Calretinin protein in Western blots.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse and non-Human Primates.
Species reactivity (tested):Rat.

Purification: Protein A Chromatography.

Immunogen: Purified Guinea pig Calretinin.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/1000. Immunohistochemistry: 1/500. This antibody works well for Immunohistochemistry on Formalin or Paraformaldehydeperfused rat brain tissue sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM Tris, 100 mM NaCl.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: Calretinin (CALB2 Products)

Background: Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).Synonyms: 29 kDa calbindin, CAB29, CALB2

Gene ID: 117059

NCBI Accession: NP_446440

UniProt: P47728