CD51 antibody
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD51 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Characteristics
- Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
- Purification
- Purified
- Clone
- 13C2
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV Primary Antibody
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anti-Integrin alpha V (ITGAV) antibody
ITGAV Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 560-744) antibodyITGAV Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 775-885) antibodyITGAV Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 71-322) antibodyITGAV Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 51-150) antibodyITGAV Reactivity: Human, Mouse WB, FACS, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) antibodyITGAV Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV Reactivity: Human WB, PLA Host: Mouse Polyclonal unconjugated
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- Application Notes
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Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- CD51 / ITGAV (ITGAV Products)
- Background
- Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4)Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
- UniProt
- P06756
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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