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CD51 antibody (FITC)

ITGAV Reactivity: Human FACS Host: Mouse Monoclonal 13C2 FITC
Catalog No. ABIN371553
  • Target See all CD51 (ITGAV) Antibodies
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reactivity
    • 94
    • 51
    • 22
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 31
    • 9
    Mouse
    Clonality
    • 56
    • 47
    Monoclonal
    Conjugate
    • 54
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51 antibody is conjugated to FITC
    Application
    • 47
    • 46
    • 29
    • 26
    • 22
    • 15
    • 14
    • 14
    • 11
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Characteristics
    Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
    Clone
    13C2
    Isotype
    IgG1
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  • Application Notes
    Flow Cytometry: 10 μL/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Alternative Name
    CD51 / ITGAV (ITGAV Products)
    Background
    Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4)Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
    UniProt
    P06756
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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