For best experience we recommend to activate Javascript in your browser.

CD28 antibody

CD28 Reactivity: Mouse FACS, IP, Func Host: Hamster Monoclonal PV-1 unconjugated

Catalog No. ABIN370909

Datasheet as PDF

Target See all CD28 Antibodies

CD28
Reactivity
165

114

50

37

23

16

12

12

7

7

6

6

1

1

1

1
Mouse
Host
137

69

27

16

12

3

2
Hamster
Clonality
198

61

4
Monoclonal
Conjugate
100

32

29

20

13

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This CD28 antibody is un-conjugated
Application
211

86

56

48

37

36

31

26

21

17

13

7

6

6

5

5

4

4

4

4

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Characteristics

Synonyms: TP44, T-cell-specific surface glycoprotein CD28

Purification

Purified

Clone

PV-1

Isotype

IgG

Top Product

Discover our top product CD28 Primary Antibody
anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reactivity: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Host: Mouse Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
CD28 Reactivity: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Host: Mouse Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reactivity: Rat FACS, IP Host: Mouse Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reactivity: Rat FACS Host: Mouse Monoclonal JJ319 PE

anti-CD28 (CD28) (C-Term) antibody
CD28 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

anti-CD28 (CD28) antibody (PerCP)
CD28 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CD28-2 APC

Application Notes

Flow Cytometry. (Ref.8-10)Immunoprecipitation. (Ref.8)Functional Assay: In vitro costimulation of T cells and NK cells. (Ref.8,9)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date

12 months
Target

CD28

Alternative Name

CD28 (CD28 Products)

Background

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. (Ref.5) CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.6-9)Synonyms: T-cell-specific surface glycoprotein CD28, TP44

UniProt

P31041

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response