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CD19 antibody (APC-Cy5.5)

CD19 Reactivity: Mouse FACS Host: Mouse Monoclonal MB19-1 APC-Cy5.5
Catalog No. ABIN370855
  • Target See all CD19 Antibodies
    CD19 (CD19 Molecule (CD19))
    Reactivity
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    Mouse
    Host
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    Mouse
    Clonality
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    Monoclonal
    Conjugate
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    This CD19 antibody is conjugated to APC-Cy5.5
    Application
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    Flow Cytometry (FACS)
    Specificity
    This antibody is specific to CD19 B cell differentiation antigen (Mr. 95 kDa).
    Characteristics
    Synonyms: Leu-12, B-cell marker, Differentiation antigen CD19, B-lymphocyte surface antigen B4
    Immunogen
    CD19+ mouse pre-B cell line, 300. 19. (Ref. 1)
    Clone
    MB19-1
    Isotype
    IgA
    Top Product
    Discover our top product CD19 Primary Antibody
  • Application Notes
    Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.1-3)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CD19 (CD19 Molecule (CD19))
    Alternative Name
    CD19 (CD19 Products)
    Background
    CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220+/CD43+/HSA+) through fully differentiated B cell stages. (Ref.1-7) Terminally differentiated plasma cells do not express CD19.1 In humans, the CD19 Molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. (Ref.3,4) All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. (Ref.1,7) Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. (Ref.7)Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    Gene ID
    12478
    UniProt
    P25918
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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