CD11b antibody (PE)
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Characteristics
- Synonyms: Integrin alpha-M, CR3A, MAC-1, MAC1, CR-3 alpha chain, Cell surface glycoprotein MAC-1subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11antigen-like family member B
- Immunogen
- Peritoneal macrophages from C57 B1/6 x DBA/2 F1 hybrid mice. (Ref. 1)
- Clone
- 3A33
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGAM Primary Antibody
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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated
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- Application Notes
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Flow Cytometry: < / = 0.3 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b (ITGAM Products)
- Background
- CD11b (Integrin alpha M subunit) combines with CD18 (Integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). (Ref.2-6) Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. (Ref.2,7-10) In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process. (Ref.4,11) Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. (Ref.12)Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
- UniProt
- P05555
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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