SPRY4 antibody (pTyr75)

Catalog No. ABIN358511

Product Details anti-SPRY4 Antibody

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Binding Specificity: pTyr75

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRY4 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody detects SPRY4 pTyr75.

Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y75 of human SPRY4.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SPRY4

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Alternative Name: Sprouty Homolog 4 / SPRY4 (SPRY4 Products)

Synonyms: SPRY4 antibody, LOC100218545 antibody, HH17 antibody, A030006O18Rik antibody, sprouty4 antibody, sprouty RTK signaling antagonist 4 antibody, sprouty (Drosophila) homolog 4 antibody, sprouty homolog 4 (Drosophila) antibody, Spry4 antibody, SPRY4 antibody, spry4 antibody

Background: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.Synonyms: Sprouty 4, Spry-4

Molecular Weight: 32541 Da

Gene ID: 81848, 9606

UniProt: Q9C004