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LEO1 antibody (pSer10)
LEO1
Reactivity: Human
EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LEO1 Antibody
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Target
See all LEO1 Antibodies
LEO1
(Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))
Binding Specificity
All epitopes for LEO1 antibodies
pSer10
Reactivity
All reactivities for LEO1 antibodies
Human
Host
All hosts for LEO1 antibodies
Rabbit
Clonality
All clonalities for LEO1 antibodies
Polyclonal
Conjugate
All conjugates for LEO1 antibodies
This LEO1 antibody is un-conjugated
Application
All applications for LEO1 antibodies
Enzyme Immunoassay (EIA)
Specificity
This antibody detects LEO1 pSer10.
Purification
Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human LEO1.
Isotype
Ig Fraction
Top Product
Discover our top product LEO1 Primary Antibody
Alternatives
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anti-Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1) (N-Term) antibody
LEO1
Reactivity: Human, Rat, Mouse, Horse, Rabbit, Dog, Guinea Pig, Monkey, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target Details for LEO1
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Target
LEO1
(Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))
Alternative Name
LEO1 (LEO1 Products )
Background
The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.Synonyms: LEO-1, RDL, RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein
Molecular Weight
75273 Da
Gene ID
123169, 9606
UniProt
Q8WVC0
Pathways
Stem Cell Maintenance
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