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PCNA antibody (C-Term)

PCNA Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN358006
  • Target See all PCNA Antibodies
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Binding Specificity
    • 16
    • 16
    • 16
    • 15
    • 11
    • 11
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 210
    • 150
    • 149
    • 54
    • 28
    • 27
    • 21
    • 19
    • 19
    • 18
    • 17
    • 14
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 134
    • 89
    • 3
    Rabbit
    Clonality
    • 134
    • 91
    • 1
    Polyclonal
    Conjugate
    • 107
    • 16
    • 12
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCNA antibody is un-conjugated
    Application
    • 186
    • 68
    • 61
    • 60
    • 51
    • 47
    • 46
    • 40
    • 29
    • 15
    • 15
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects PCNA (C-term).
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCNA Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Alternative Name
    PCNA (PCNA Products)
    Background
    PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Synonyms: Cyclin, Proliferating Cell Nuclear Antigen
    Molecular Weight
    28769 Da
    Gene ID
    5111, 9606
    UniProt
    P12004
    Pathways
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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