ERVW-1 antibody (Middle Region)

Catalog No. ABIN357849

Product Details anti-ERVW-1 Antibody

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERVW-1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ERVWE1 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ERVWE1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ERVW-1

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Alternative Name: ERVWE1 (ERVW-1 Products)

Background: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.Synonyms: Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q21.2 provirus ancestral Env polyprotein, Syncytin, Syncytin-1

Molecular Weight: 59866 Da

Gene ID: 30816, 9606

UniProt: Q9UQF0