EIF2B3 antibody (C-Term)

Catalog No. ABIN357251

Product Details anti-EIF2B3 Antibody

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects EIF2B3 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of Human EIF2B3. Genename: EIF2B3

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for EIF2B3

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Alternative Name: EIF2B3 (EIF2B3 Products)

Synonyms: zgc:56473 antibody, 1190002P15Rik antibody, EIF-2B antibody, EIF2Bgamma antibody, eukaryotic translation initiation factor 2B subunit gamma L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma antibody, eukaryotic translation initiation factor 2B subunit gamma antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antibody, eukaryotic translation initiation factor 2B, subunit 3 antibody, eif2b3.L antibody, eif2b3 antibody, EIF2B3 antibody, Eif2b3 antibody

Background: EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.Synonyms: Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma

Molecular Weight: 31511 Da

Gene ID: 8891

NCBI Accession: NP_065098

UniProt: Q9NR50