GJB6 antibody (N-Term)

Catalog No. ABIN357095

Product Details anti-GJB6 Antibody

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Binding Specificity: AA 95-124, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects GJB6 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 95~124 amino acids from the N-terminal region of Human GJB6.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for GJB6

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Alternative Name: GJB6 / Cx30 (GJB6 Products)

Background: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.Synonyms: Connexin-30, Gap junction beta-6 protein

Molecular Weight: 30387 Da

Gene ID: 10804, 9606

UniProt: O95452

Pathways: Sensory Perception of Sound