VEGFC antibody (C-Term, N-Term)

Catalog No. ABIN356356

Product Details anti-VEGFC Antibody

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Binding Specificity: C-Term, N-Term

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGFC antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to VEGFC.

Characteristics: Synonyms: VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growthfactor-related protein, Flt4 ligand

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This monoclonal antibody is generated from mice immunized with three KLH conjugatedsynthetic peptides selected from the N-terminal, central, and C-terminal regions of humanVEGF3.

Clone: 30AT1174-77

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/1,000Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: VEGF-C / Flt4-L (VEGFC Products)

Background: VEGF-C (VEGF3) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein

Gene ID: 7424

UniProt: P49767

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2