CXCR4 antibody (AA 17-42)

Catalog No. ABIN342739

Product Details anti-CXCR4 Antibody

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Binding Specificity: AA 17-42

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Peptide sequence is <50 % identical to other human chemokine receptors in this region. This antibody was not tested for cross-reactivity to mouse CXCR4.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee (100%) Gorilla, Orangutan, Gibbon, Siamang (96%) Macaque, Monkey, Titi monkey, Green monkey, Squirrel monkey, Baboon, Bat, Dog, Tamarin (88%) Marmoset, Mangabey, Sheep, Elephant, Panda, Bovine, Cat, Rabbit (85%) Porcine, Horse (81%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to N-terminal extracellular domain of human CXCR4 receptor. Percent identity by BLAST analysis: Human, Chimpanzee (100%), Gorilla, Orangutan, Gibbon, Siamang (96%), Macaque, Monkey, Titi monkey, Green monkey, Squirrel monkey, Baboon, Bat, Dog, Tamarin (88%), Marmoset, Mangabey, Sheep, Elephant, Panda, Bovine, Cat, Rabbit (85%), Porcine, Horse (81%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA (1:25000), IHC, IHC-P (1:150), WB (1:250)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Phosphate buffered saline, 1 mg/mL BSA, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Short term: -20°C
Long term: -70°C
Avoid freeze-thaw cycles.

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4 (CXCR4 Products)

Background: Name/Gene ID: CXCR4
Subfamily: Chemokine
Family: GPCR

Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR

Gene ID: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events