p53 antibody (N-Term)
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- Target See all p53 (TP53) Antibodies
- p53 (TP53) (Tumor Protein P53 (TP53))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This p53 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Specificity
- Recognizes an epitope within aa 20-25 at the N-terminus of human p53. p53 is a nuclear protein and tumor suppressor that is mutated in a wide variety of cancers. It mediates cell cycle arrest in response to DNA damage, making it important in the maintenance of genomic stability.
- Purification
- Protein G purified
- Immunogen
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Recombinant human p53 expressed in E. coli.
Type of Immunogen: Recombinant protein - Isotype
- IgG2a
- Top Product
- Discover our top product TP53 Primary Antibody
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- Application Notes
- Approved: ELISA (1 - 5 μg/mL), IHC, IP, WB
- Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -70°C, avoid freeze/thaw cycles.
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Alternative Name
- TP53 / p53 (TP53 Products)
- Background
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Name/Gene ID: TP53
Family: P53
Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1 - Gene ID
- 7157
- UniProt
- P04637
- Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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